Articles breast cancer and genetics



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Renwick et al. Although there have been tremendous advances in elucidating genetic risk factors underlying both familial and sporadic breast cancer, much of the genetic contribution to breast cancer etiology remains unknown. An excess of truncating mutations in all three genes was found in cases, although the total number of cases with deleterious mutations was only 11 [ 54 ] dissertation; not peer reviewed. Cancer incidence and mortality worldwide: Breast cancer, like all complex diseases, results from genetic factors, environmental factors, and interactions between the two.

Articles breast cancer and genetics
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Hodgkin lymphoma ILCB: These results are quite sobering, given the enormous sample size needed to discover only a single rare variant, as well as the ad-hoc criteria employed for variant selection. Identifying novel constrained elements by exploiting biased substitution patterns.

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