PLoS One. Several groups advocated for the use of SLNB prior to chemotherapy, whereas others advocated for SLNB after chemotherapy to reduce the number of axillary dissections needed in those with clinically node-positive disease downstaged with systemic therapy. At a median follow-up of 8. Arch Surg. Physical and psychological morbidity after axillary lymph node dissection for breast cancer.
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Contemporary Management of the Axilla in Breast Cancer
Study information Scientific title Axillary surgery trial for breast cancer Acronym Study hypothesis Not provided at time of registration Ethics approval Not provided at time of registration Study design Randomised controlled trial Primary study design Interventional Secondary study design Randomised controlled trial Trial setting Hospitals Trial type Treatment Patient information sheet Condition Breast cancer Intervention 1. Sentinel-node biopsy to avoid axillary dissection in breast cancer with clinically negative lymph-nodes. Additional data are needed before broader adoption of this approach is routinely extended to patients undergoing mastectomy. These axillary surgery trial for breast cancer are randomly assigned to nodal irradiation or observation. Recent studies have demonstrated that the extent of surgical intervention in both the breast and axilla can be minimized through a personalized approach based on breast cancer stage, subtype, and planned adjuvant therapies.
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Axillary surgery trial for breast cancer
The TAXIS trial is designed to fill this gap by examining in particular the value of tailored axillary surgery TASa new technique for selectively removing positive lymph nodes. Twenty-year follow-up of a randomized trial axillary surgery trial for breast cancer total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. Patients undergoing mastectomy who are randomly assigned to regional radiation will also receive treatment to the chest wall.